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Ece Karatan
karatane@appstate.edu
Appalachian State University
Department of Biology
Rankin Science North
319 (Office), 303 (Lab)
828-262-6742
Disclaimer |
Karatan Lab is located in the Department of Biology at Appalachian State University. The main focus of the reseach in our lab is biofilm formation in Vibrio cholerae.
![](Images/12-13/karatanlab_1213.jpg)
Karatan lab 2012-2013. Back row-left to right: Stormtrooper, Jacob Hoyle, Jessie Wozniak, Randy Cockerell, Tony Angotti, Princess Leia. Front row-left to right:Allison Gardzalla, Ece Karatan
We are always looking for enthusiastic graduate and undergraduate students to join the lab. Funding for a Master's degree is available to graduate students in the form of teaching assistantships and various fellowships. Currently, we are looking for one or two graduate students for a partially NIH-funded position. In addition, opportunities may be available for undergraduate students to do research in the lab for independent study credit or credit towards the University and/or Departmental Honors program. If you are interested in joining the Karatan Lab please contact Ece Karatan.
Lab News:
April 2012: Brad gets accepted into the post-baccalaureate program in biomedical sciences at Edward Via Virginia College of Osteopathic Medicine
March 2012 : Alex gets accepted into the PhD program in Biomedical Sciences at Medical University of South Carolina
February 2012: Sam gets accepted into the PhD program in Molecular and Cellular Biosciences at Wake Forest University
January 2012: Zach, Sam, and Marcus's NspC paper published online in FEMS Microbiology Letters
August 2011: Ece receives NIH grant (R15) from the Institute of Allergy and Infectious Diseases
January 2011: Krissy's paper gets accepted in Geomicrobiology
Previous years' lab members:
11-12
10-11
09-10
08-09
07-08
06-07
Selected publications:
Elevated levels of the norspermidine synthesis enzyme NspC enhance Vibrio cholerae biofilm formation without affecting intracellular norspermidine concentrations. (2012) FEMS Microbiol Lett 329 (1):18-27
Increased abundance of Gallionella spp., Leptothrix spp., and total bacteria in response to enhanced Mn and Fe concentrations in a disturbed southern Appalachian high elevation wetland. Johnson, KW., McDonald, W., Carmichael, MJ., Pitchford, J., Windelspecht, M., Karatan, E.., and Brauer, SL. (2012) Geomicrobiology Journal 29 (2):124-138
Spermidine regulates Vibrio cholerae biofilm formation via transport and signaling pathways. McGinnis MW, Parker ZM, Walter NE, Rutkovsky AC, Cartaya-Marin C, Karatan E. (2009) FEMS Microbiol Lett 299(2):166-74.
Signals, regulatory networks, and materials that build and break bacterial biofilms. Karatan E., Watnick, PI. (2009) Microbiol Mol Biol Rev 73: 310-347.
NspS, a predicted polyamine sensor, mediates activation of Vibrio cholerae biofilm formation by norspermidine. Karatan E., Duncan, T., Watnick PI. (2005) J Bacteriol 187: 7434-7443.
Biofilm Development in Bacteria. Kierek-Pearson K. and Karatan E. (2005). In: Advances in Applied Microbiology, Laskin, AI., Bennett, JW., and Gadd, MG. (Ed) Elsevier Inc. Vol. 57 pp. 79-112
Role for glycine betaine transport in Vibrio cholerae osmoadaptation and biofilm formation within microbial communitiesKapfhammer D., Karatan E., Pflughoeft K.J., Watnick P.I. (2005) Appl. Environ. Microbiol. Jul; 71(7):3840-7.
Antibody Arrays Prepared by Cutinase-Mediated Immobilization on Self-Assembled Monolayers. Kwon Y., Han Z., Karatan E., Mrksich M., Kay B.K. (2004) Anal. Chem. Oct 1;76(19):5713-20.
Molecular Recognition Properties of FN3 Monobodies that Bind the Src SH3 Domain. Karatan E., Merguerian M., Han Z., Scholle MD., Koide S., Kay BK. (2004) Chem. Biol. Jun;11(6):835-44
Accelerated Screening of Phage-Display Output with Alkaline Phosphatase Fusions. Han Z., Karatan E., Scholle MD., McCafferty J., Kay BK. (2004) Comb. Chem. High Throughput Screen. Feb; 7 (1): 55-62
Effect of Loss of CheC and Other Adaptational Proteins on Chemotactic Behaviour in Bacillus subtilis. Saulmon MM., Karatan E., Ordal GW. (2004) Microbiology; (150): 581-589
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